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A rune is a type of upgrade component for armor and bags. Unless otherwise specified, all instances of the word "rune" in this article refer specifically to armor runes. The only rune applicable to bags is a Rune of Holding. Runes drop in all campaigns and must be extracted from salvage items. Runes can also be purchased from Rune Traders.
The positive effects of such runes do not stack with the effects of runes of the same attribute - the larger effect takes precedence. The negative effects of equipping several runes of the same attribute do stack… Read more.